The drug contains 4 testosterone esters, which have different speed of action. In men, testosterone is necessary for the functioning of the gonads, the formation of the external genital organs, the prostate gland, seminal vesicles, secondary sexual characteristics (male tone of voice, male-pattern hairiness, etc.). In the female body, testosterone acts as an antagonistic to estrogen. Has a positive effect in climacteric disorders.
Omnadren 250 is a mixture of testosterone esters, which, after administration, are slowly absorbed at different rates, which allows maintaining a relatively constant level of testosterone in the blood. The drug is prescribed at intervals of 4 weeks. In the blood, almost 98% of testosterone binds to a specific fraction of globulins that binds testosterone and estradiol. Biotransformation occurs in the liver to various 17-ketosteroids, which, after conjugation with glucuronic or sulfuric acid, are excreted in the urine (approximately 90%). About 6% of the absorbed drug is excreted in the feces unbound. The half-life of testosterone is 10–100 minutes.