Nebido 1000 mg Bayer

 

Information for those wishing to buy Nebido 1000 mg in the UK

Nebido 1000 mg from Bayer is an intramuscular depot preparation containing testosterone undecanoate. For this reason, there is no first pass effect. After an intramuscular injection of the oily testosterone undecanoate solution, it is gradually released from the depot and is almost completely broken down by serum esterases into testosterone and undecanoic acid. An increase in serum testosterone concentration from baseline can be detected on the day after injection.

Nebido is a trade name for the castor oil ester of testosterone undecanoate (carbon atom count 11). It is manufactured by Bayer Pharmaceuticals AG (Germany). The half-life of nebido is long and is about 8 weeks. In ANGLI a rather new preparation of “long” testosterone in connection with use in structure of a preparation of testosterone undecanoate and a basis – castor oil, it is distinguished by a smooth plateau of testosterone level within 30 days, smoothly decreasing by 45 day from an injection. In two separate studies the mean testosterone Cmax values of 24 and 45 nmol/l were determined 14 and 7 days after a single injection of 1000 mg testosterone undecanoate, respectively. Post-maximal testosterone levels were reduced, with a T1/2 of approximately 53 days.

Effects of using Nebido 1000 mg by Bayer

The effects of Nebido 1000 mg can be described very simply. You no longer produce enough testosterone and as a consequence suffer from low testosterone levels. By supplementing with Nebido, you get the testosterone your body needs and all the low level symptoms associated with it disappear. Although some may find this difficult to understand, keep in mind that Nebido 1000 mg is simply testosterone, the very hormone your body needs. It may be a synthetic model, but once in the body, the body will have no distinction between it and the naturally produced testosterone hormone.

Because of the effects of Nebido, or more specifically the effects of exogenous testosterone, those who suffer from low testosterone levels will have their symptoms disappear soon after taking it. There are many possible symptoms of low testosterone. Most men show only one or two in the early stages of the disease, but over time the symptoms usually increase and gradually become more severe. The main symptoms of low testosterone that can be corrected with Nebido by Bayer include:

• Erectile dysfunction (inability to maintain or get an erection)
• Loss of libido (can refer to partial or complete loss)
• Loss of muscle mass (despite diet and exercise)
• Loss of strength (despite diet and exercise)
• Increase in body fat (despite diet and exercise)
• Inability to lose fat (despite diet and exercise)
• Decreased memory
• Decreased mental concentration
• Decreased mental clarity
• Sluggishness
• Irritability
• Weakened immune system
• High cholesterol
• Loss of hair
• Depression
• Reduced energy
• Insomnia

Indications for Nebido 1000 mg from Bayer

Testosterone Nebido is responsible for the formation of male characteristics during foetal development and early childhood as well as during puberty, and thereafter for the maintenance of the male phenotype and androgen dependent functions (e.g. spermatogenesis, gonads). Insufficient testosterone secretion leads to male hypogonadism, which is characterised by low serum concentrations of testosterone.

Symptoms associated with male hypogonadism include erectile dysfunction, decreased libido, fatigue, depressed mood, absence, underdevelopment or regression of secondary sexual characteristics, and increased risk of osteoporosis, among others. Exogenous androgens are prescribed to increase insufficient endogenous testosterone levels and to reduce the symptoms of hypogonadism.